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Accuracy of immunoglobulin M and immunoglobulin A of saliva in early diagnosis of dengue: Systematic Review and Meta-analysis Anais da ABC (AABC)
COLONETTI,TAMY; ROCHA,BELISE V.E.; GRANDE,ANTÔNIO J.; ALEXANDRE,MARIA C.M.; DONDOSSOLA,EDUARDO R.; MADEIRA,KRISTIAN; ROSA,MARIA I..
ABSTRACT The objective of the study was to conduct a systematic review to synthesize the current evidence on the accuracy of IgM and IgA to early diagnosis the dengue virus. The review protocol was registered at PROSPERO (CRD 42015024808). We searched for studies in the following electronic database from 1990 to January 2018. The search identified 3507 studies. Five studies were included for quantitative analysis. Three studies included evaluations of salivary IgM provided a sensitivity of 86% and specificity of 93%. Two studies included evaluating of IgA salivary showed a combined sensitivity of 69% and a combined specificity of 98%. Despite the results found and the low methodological quality of the studies included in the meta-analysis it is still soon...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunoglobulin M; Immunoglobulin A; Antibodies; Dengue virus; Diagnosis..
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000603147
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Neurotrophins, cytokines, oxidative parameters and funcionality in Progressive Muscular Dystrophies Anais da ABC (AABC)
COMIM,CLARISSA M.; MATHIA,GISIANE B.; HOEPERS,ANDREZA; TUON,LISIANE; KAPCZINSKI,FLÁVIO; DAL-PIZZOL,FELIPE; QUEVEDO,JOÃO; ROSA,MARIA I..
We investigated the levels of brain derived-neurotrophic factor (BDNF), cytokines and oxidative parameters in serum and tried to correlate them with the age and functionality of patients with Progressive Muscle Dystrophies (PMD). The patients were separated into six groups (case and controls pared by age and gender), as follows: Duchenne Muscular Dystrophy (DMD); Steinert Myotonic Dystrophy (SMD); and Limb-girdle Muscular Dystrophy type-2A (LGMD2A). DMD patients (±17.9 years old) had a decrease of functionality, an increase in the IL-1β and TNF-α levels and a decrease of IL-10 levels and superoxide dismutase activity in serum. SMD patients (±25.8 years old) had a decrease of BDNF and IL-10 levels and superoxide dismutase activity and an increase of IL-1β...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Progressive Muscular Dystrophies; BNDF; Cytokines; Oxidative stress.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000401809
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